XyHTeP Posted June 20, 2005 Report Share Posted June 20, 2005 (edited) U headlinesu na BBS sam na blic video vest da su neki naucnici otkrili da IBUPROFEN kod nas distribuiran kao BRUFEN povecava rizik od srcanog napada za 24%. Pokusao sam na brzinu da izguglam, ali bez uspeha. Mozda neko ima neki info. inace sa wikipedi: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the symptoms of arthritis, primary dysmenorrhoea, fever; and as an analgesic, especially where there is an inflammatory component. Ibuprofen was developed by the research arm of Boots. It is widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen. ... Adverse effects Ibuprofen appears to have the lowest incidence of gastrointestinal adverse drug reactions (ADRs) of all the non-selective NSAIDs. However, this only holds true at lower doses of ibuprofen, so over-the-counter preparations of ibuprofen are generally labelled to advise a maximum daily dose of 1.2 grams. Reported ADRs Common adverse effects include: nausea, dyspepsia, gastrointestinal ulceration/bleeding, raised liver enzymes, diarrhoea, headache, dizziness, salt and fluid retention, hypertension (Rossi, 2004). Infrequent adverse effects include: oesophageal ulceration, heart failure( ali cak 24%???), hyperkalaemia, renal impairment, confusion, bronchospasm, rash (Rossi, 2004) Edited June 20, 2005 by XyHTeP Quote Link to comment Share on other sites More sharing options...
Wulfgar Posted June 20, 2005 Report Share Posted June 20, 2005 (Rossi, 2004) Daj josh neshto. Kapiram da je studija radjena na starijim osobama koji zajedno imaju prosek od 3+ infarkta po choveku. Samo ti pij svoj brufen... i sve ostale lekice koji su ti prepisani. Quote Vulfi sam kroji svoju odecu od kozhe ubijenih protivnika. Pr0 wifebeaters know. Never give up. Never give in. Link to comment Share on other sites More sharing options...
Spu [RuR] Posted June 20, 2005 Report Share Posted June 20, 2005 ja sam to uzimao samo dvaput u zhivotu, poslednji put sad pre tri dana zbog zuba, stavljen mi je lek direktno na zhivac pa jebe kevu. I to uzmem bash 1.2 grama i ubije sav bol, lekic rula =) Quote Everytime I cross the line I push the boundaries out a little... Link to comment Share on other sites More sharing options...
XyHTeP Posted June 20, 2005 Author Report Share Posted June 20, 2005 (edited) Samo ti pij svoj brufen... i sve ostale lekice koji su ti prepisani. burned :) Zabrinuo sam se, kad nemam psycho na gajbi prvi painkiller za koji se uvatim je brufen Edited June 20, 2005 by XyHTeP Quote Link to comment Share on other sites More sharing options...
_Silent_ Posted June 20, 2005 Report Share Posted June 20, 2005 uhh... te brufene neke devojke koje znam piju nenormalno... ma, gde moze da bude ikada korisno da pijesh ijedan jak lek... ne volim ni andole... Quote Link to comment Share on other sites More sharing options...
Sharulja Posted June 20, 2005 Report Share Posted June 20, 2005 Brufen je protiv temperature M A J K A !!! pijem ga od kako znam za sebe i za temperaturu)imao sam fras kao mali i od tad u proseku 1 u 2 meseca imam temperaturu...) Brufen konza... Quote Arbeit macht Frei. Link to comment Share on other sites More sharing options...
Sajro Posted June 20, 2005 Report Share Posted June 20, 2005 ja patim od migrene & stuff.. od svih lekova koje sam probao (za bolove) najbolje mi pomogne brufen. od 14. godine pijem bar po 2x 400mg na dan i josh nisam dobio srchani napad! :) inache chuo sam da su pocheli da prave, to jest da se prodaje kod nas, i brufen od 700mg.. jeee... :)) Quote Link to comment Share on other sites More sharing options...
Dule_smor Posted June 20, 2005 Report Share Posted June 20, 2005 Brufen deluje kao ihibitor enzima ciklooksigenaze u metabolickom putu arahidonske kiseline u kome izmedju ostalog nastaju razne vrste prostangladina.Prostangladina ima mnogo vrsta i imaju razne uloge-medijatori zapaljenja, menjaju tonus krvnih sudova i jako su bitni za funkciju trombocita.E sad posto brufen inhibira stvaranje prostangladina to smanjuje zapaljenjsku reakciju i to mu je jedna od glavnih primena.Ali to takodje smanjuje funkciju trombocita i moze da dovede do krvarenja-zato je loshe cesto ga uzimati. A sto se srcanog udara tice to ne znam zaista.Moguce je da hiperkalijemija koju on izaziva(mada ne znam u kojoj je to meri) moze da izazove poremacaje sprovodnog sistema srca ili cak prestanak rada srca, ali to se desava kad je koncentracija kalijuma prevelika.Sto se tice dejstva na bubrege i zadrzavanje elektrolita i posledicnu hipertenziju koja svakako steti srcu, takodje ne znam da li je to dejstvo toliko izrazeno. Toliko od mene, jos nemam farmakologiju na faksu, tako da ostavljam kolegi Koletu dalja objasnjenja i eventualne ispravke:). Quote Link to comment Share on other sites More sharing options...
Dz Posted June 22, 2005 Report Share Posted June 22, 2005 Meni je brufen najbolji za bolove Quote oO Link to comment Share on other sites More sharing options...
Sajro Posted June 22, 2005 Report Share Posted June 22, 2005 Meni je brufen najbolji za bolove ← nego shta nego jeste. sve zivo sam probao, ali uvek se vratim na 2x 400mg brufena! ;) Quote Link to comment Share on other sites More sharing options...
Debeli Posted June 29, 2005 Report Share Posted June 29, 2005 Meni je brufen najbolji za bolove ← novalgetol trodon morfin Quote MORTALIS HOMO AURA PER KHARONE SERVAStyle over subsistenceCrown of Light. Keeper of The Yoda Chamber. I&I, Righteous Army of One. Link to comment Share on other sites More sharing options...
iguana Posted June 29, 2005 Report Share Posted June 29, 2005 (edited) Brufen deluje kao ihibitor enzima ciklo.... ← I've lost you somewhere around here... Edited June 29, 2005 by iguana Quote It's nice to be good, but it's nothing compared to being bad Link to comment Share on other sites More sharing options...
Dule_smor Posted June 30, 2005 Report Share Posted June 30, 2005 Pa slican andolu...ali ako bas preteras moze da sjebe trombocite...kao ti recimo sa tih 200 grama;). Quote Link to comment Share on other sites More sharing options...
phantomq Posted July 1, 2005 Report Share Posted July 1, 2005 ibuprofen (brufen) je kontraindikovan samo kod ljudi sa srcanom isuficijencijom i kod njih moze da izizove "infrakt" Tako da mozete da nastavite da se drogirate Quote ((((Q)))) SRBI su najgluplji narod na svetu!!! Link to comment Share on other sites More sharing options...
urgh Posted July 1, 2005 Report Share Posted July 1, 2005 novalgetolto nije za ljude vec za konje:) Quote No one can survive becoming a legend.i ja kazem jebiga! Kao da je jebiga neka magichna rech. Link to comment Share on other sites More sharing options...
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