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Preparat protiv raka


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Ispituju preparat protiv raka

25. jun 2009. | 01:02 | Izvor: Večernje novosti

Beograd -- Tim stručnjaka kragujevačkog Medicinskog fakulteta već četiri godine radi na preparatu protiv raka, koji zasad daje dobre rezultate, pišu “Večenje novosti”.

Zasad se obavljaju "in vitro" (u staklu) laboratorijska ispitivanja preparata, ali su kragujevački stručnjaci - dr Suzana Popović, dr Nebojša Arsenijević i dr Dejan Baskić - i dalje oprezni i nisu spremni da potvrde da su pronašli siguran lek protiv maligniteta. Ipak, rezultati do kojih su došli su ohrabrujući.

“Ispitujući prirodne supstance, koje sadrže med, polen, ekstrate odabranog bilja, dobili smo preparate koji ubijaju samo maligne ćelije, koje imaju selektivno dejstvo, dakle ne oštećuju zdrave ćelije u organizmu”. kaže dr Suzana Popović.

Profesor Nebojša Arsenijević, dekan Medicinskog fakulteta, kaže da su potrebna dalja ispitivanja, takozvane multicentralne kliničke studije, kako bi se novi lek uveo u takozvanu široku upotrebu. A za to je, kako navodi, potrebno i mnogo novca.

Ispitivanja su počela na inicijativu "Biofarm grupe" i bolnice "Nova vita", koja godinama koristi prirodne preparate za lečenje pacijenata.

Psihijatar Prvoslav Marković, član istraživačkog projekta, ne krije da su ga obradovali nalazi stručnjaka iz Instituta za nuklearne nauke "Vinča" i kragujevačkih eksperata.

On kaže da ni stručnjaci pomenutih ustanova nisu u početku prihvatili lek, ali su za razliku od drugih ustanova, ipak saslušali, a potom i ispitali delotvornost preparata kojim su izlečeni mnogobrojni pacijenti.

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Page last updated at 23:09 GMT, Wednesday, 24 June 2009 00:09 UK

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New cancer drug 'shows promise'

Breast cancer cells

The treatment was tested on breast cancer patients

Researchers say a new type of cancer treatment has produced highly promising results in preliminary drug trials.

Olaparib was given to 19 patients with inherited forms of advanced breast, ovarian and prostate cancers caused by mutations of the BRCA1 and BRCA2 genes.

In 12 of the patients - none of whom had responded to other therapies - tumours shrank or stabilised.

The study, led by the Institute of Cancer Research, features in the New England Journal of Medicine.

CASE STUDY

Julian Lewis

Julian Lewis, 62, was treated with olaparib after being diagnosed with advanced prostate cancer.

Within a month or two levels of a key chemical marker of cancer went down to a low level, and have now stayed low for more than two years.

In addition, secondary tumours in his bones have almost disappeared.

He has experienced minor side-effects, such as stomach discomfort and mild nausea, but he said: "I hope to carry on with this for as long as possible.

Partly the aim is the obvious one of keeping my cancer cells in check, but there's a broader goal too: to help find out how long this drug can be used safely in other people."

One of the first patients to be given the treatment is still in remission after two years.

Olaparib - a member of a new class of drug called PARP inhibitors - targets cancer cells, but leaves healthy cells relatively unscathed.

The researchers, working with the pharmaceutical company AstraZeneca, found that patients experienced very few side-effects, and some reported the treatment was "much easier than chemotherapy".

Researcher Dr Johann de Bono said the drug should now be tested in larger trials.

He said: "This drug showed very impressive results in shrinking patients' tumours.

"It's giving patients who have already tried many conventional treatments long periods of remission, free from the symptoms of cancer or major side-effects."

Olaparib is the first successful example of a new type of personalised medicine using a technique called "synthetic lethality" - a subtle way of exploiting the body's own molecular weaknesses for positive effect.

In this case the drug takes advantage of the fact that while normal cells have several different ways of repairing damage to their DNA, one of these pathways is disabled by the BRCA mutations in tumour cells. .....

http://news.bbc.co.uk/2/hi/health/8116790.stm

Nije isti tip leka ali rade na sve strane samo sto nas naravno nije dospeo do bbc-ja, nadam se da nasi budu prvi koji ce naci lek,,mada i nije bitno ko ce prvi naci lek vec samo da se pronadje lek protiv raka koji radi.....

/ignore.

neki ljudi ne razumu neke stvari!1!

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New cancer treatment shows 'great promise'

By Clive Cookson in London, Financial Times, 24 Jun 2009

A new way of treating cancer has shown "great promise" in its first clinical trial at the Royal Marsden Hospital in London.

Researchers gave olaparib, a drug being developed by AstraZeneca with the UK Institute for Cancer Research, to 60 patients with advanced breast, ovarian and prostate cancers. All had mutations in the BRCA1 and BRCA2 genes associated with inherited forms of these cancers.

"This drug showed very impressive results in shrinking patients' tumours," said Dr Johann de Bono of the ICR. "It is giving patients who have already tried many conventional treatments long periods of remission, free from the symptoms of cancer or major side-effects."

The results, which have caused a buzz at recent cancer conferences, were published on Wednesday night in the New England Journal of Medicine, the leading US medical journal.

Olaparib kills cancer cells but leaves healthy cells relatively unscathed. The drug blocks an enzyme called Parp, which is involved in repairing DNA defects in human cells. Healthy cells can mend their DNA through alternative biological pathways, but cancer cells carrying the BRCA1 and BRCA2 genes do not have alternative repair mechanisms – and they die in the presence of the drug.

BRCA1 and BRCA2 mutations are responsible for about 5 per cent of breast cancers – though these occur in younger women and tend to be particularly aggressive tumours. The same mutations are also implicated in some ovarian and prostate cancers.

But ICR scientists predict that olaparib and other drugs that work in the same way – known as Parp inhibitors – will also be effective against many non-BRCA cancers that have different DNA repair defects. They believe up to half of the most common type of ovarian cancers could respond to olaparib treatment.

Unlike a competing Parp inhibitor being developed by France's Sanofi-Aventis, which is injected into patients as an adjunct to chemotherapy, olaparib has the advantage that it is taken on its own by mouth. "It is remarkably free of side-effects," Dr de Bono said.

The original research on olaparib was carried out at ICR and Sheffield University and taken up by KuDos, a Cambridge biotechnology company that AstraZeneca bought at the end of 2005 for $210m .

AstraZeneca and ICR are planning more extensive clinical trials to discover how effectively olaparib will fight a wider range of other non-BRCA cancers. "Parp inhibitors are going to change cancer medicine," said Dr de Bono.

The researchers warn that olaparib must complete several more years of testing in patients before it becomes commercially available. It will then be accompanied by a genetic test to identify patients who will benefit from the drug.

mislim ... pih

nishta razlichito od vesti u poslednjih 10 godina, sem shto nema sideeffectsa. chisto sumnjam da tjemo natji neko univerzalno reshenje za kancer u sledetjih 5 godina, vishe je verovatno, kao shto sam rekao na nekom drugom topicu da lek/vakcina za aids izadje ove ili sledetje godine. ko se razume malo u medicinu i zna kolike su nam mogutjnosti u istoj danas zna i zashto je toliko teshko natji 'lek' za kancer. pre tje biti da tjemo pre stitji do toga da pravimo genetski modifikovanu decu bez gena koji mogu da izazovu kancer.

inache nemojte da se zanosite sa tim da mi neshto izmislimo, mozhda nash chovek preko, al kod nas je istrazhivanje ravno nuli. mislim da ne moram da podsetjam koji smo tretman imali prema miodragu stojkovitju.

• crno nam se piše

• belo nam se šmrče

• mind over matter

• jebo sam vam mater

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mislim ... pih

nishta razlichito od vesti u poslednjih 10 godina, sem shto nema sideeffectsa. chisto sumnjam da tjemo natji neko univerzalno reshenje za kancer u sledetjih 5 godina, vishe je verovatno, kao shto sam rekao na nekom drugom topicu da lek/vakcina za aids izadje ove ili sledetje godine. ko se razume malo u medicinu i zna kolike su nam mogutjnosti u istoj danas zna i zashto je toliko teshko natji 'lek' za kancer. pre tje biti da tjemo pre stitji do toga da pravimo genetski modifikovanu decu bez gena koji mogu da izazovu kancer.

Ako je genetski modifikovanu dete, nije greh da ga prcam pre nego shto napuni 18?

poz voz 2011

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mislish 14 ? jbt stalno zaboravljate =))

btw nadam se da svi uvidjaju da bi lek (a pogotovo vakcina) za aids/kancer bio kontraproduktivan za farmaceutske kutje i medicinske ustanove, jer njih naravno ne zanimaju zhivoti nego samo zeleni papiritji.

• crno nam se piše

• belo nam se šmrče

• mind over matter

• jebo sam vam mater

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ko sto su rekli srba i milic...evo samo u poslednjih mesec dana nekoliko ovakvih vesti, i u mejo klinici u minesoti su kao pronasli neki lek vs karcinoma prostate...mogu da se kladim da u skorijoj buducnosti nece biti pronadjen neki "univerzalni" i stopostotni lek za kancer...

srpskivojnik-3.jpg

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Ma samo nanoboti u crvenoj piluli - ulete u organizam jednom mesechno, pojedu sve maligne celije, uklone holesterol, prochiste kapilare i izadju u vidu pu-pua na zadnja vrata posle dan-dva.

Edited by ZerBah

А в чем сила, брат?

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Pa dobro, svaki napredak je bitan. Ako ovi nasi odrade makar deo, osim sto je fino sto nesto pozitivno dolazi i iz nase zemlje, bice to super potisak za istrazivacki rad u Srbiji...tja valjda im dodele malo vise resursa (svima) za neke druge pronalaske i istrazivanja.

Bah "malo vise"... MNOGO vise, posto je sad ionako smesan nivo ulaganja.

nisam bas siguran da sa svatio tvoj post zerbah

Neki tipuju na "zapadnjacku" genetiku, dok neki, poput Zerbaha tipuju na istocnjacku nanotehnologiju. Zar nisi nikad citao Martija Misteriju i Atlantida VS Mu? :)

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koji crni istrazivacki rad kod nas, boli drzavu kurac za to...naravno, to su bitna i zanimljiva istrazivanja i sam bih voleo da se bavim imunologijom i slicnim poljima, ali mi se cini da od toga kod nas nema leba...mozda ako zapalim za japan i upadnem u ekipu koja ce pronaci lek...JAPAN DO TOKIJA!1...oh wait... :D

srpskivojnik-3.jpg

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@ZerBash :D

Bilo bi super da tako neshto postoji.

Mada cela poenta je kolko para moze da se uzme od leka koji se napravi i pusti u proizvodnju. Da li se vishe isplati da "leche" a nikad ne izleche ili potpuno izleche neku bolest pitanje je sad.

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  • 3 weeks later...

ma samo $ je bitan...

to ti je ona prica...

prvo su se ljudi palili na religiju, to je izazvalo krstaske ratove

onda su se palili na politiku, to je izazvalo prvi/drugi svetski rat

sad se ljudi pale na kesh, sami zakljucite.

znam za priche ljudi koji imaju "tudje" organe u sebi (transplantacija jelte), moraju da se kljukaju glupostima koje im ubijaju imunitet, da im organizam ne bi odbacio "uljeza" . Lekovi za tu "adaptaciju" koliko znam postoje, ali su nestvarno skupi. jebiga :)

Nema tu nista vezano za nas mentalitet vec za mentalitet interneta i foruma gde je svako jak i svakome je pisa mnogo velika pa moze da se kurci jer zna da ga nece drmnuti neka pesnica iz monitora i sasuti mu sve zube niz grlo ( mlechne zube naravno ).

ovog dakija ovnuju svuda jebote
by Pesma-Mrtve-Dece
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  • 3 months later...

Makrobiotika npr.?

Relativno jeftino, mada ti treba guru, koji se zaista razume u istu. Chitao sam i slushao da lechi sve i svashta. Odnosno, po makrobiotici, ne postoji neizlechiva bolest.

Naravno, metodi ishrane su rigorozni (u zavisnosti od faze bolesti), ali je izlechenje zagarantovano. So they say.

Shto se mene tiche, da imam rak ili tumor ili bilo koju tu bolest koja te jede iznutra, pre bih se okrenuo ka makrobiotici nego ishao na razne hemoterapije, gutao kojekakve hemije itd.

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